Structure of PDB 2o93 Chain O

Receptor sequence
>2o93O (length=287) Species: 9606 (Homo sapiens) [Search protein sequence]
ASSVPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHP
VVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEK
IVGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTR
VRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHELPMVERQDTDSCLVY
GGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVE
IPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPV
3D structure
PDB2o93 Crystal structure of NFAT bound to the HIV-1 LTR tandem kappaB enhancer element
ChainO
Resolution3.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna O Y424 T426 K520 R522 N523 R537 K538 R572 R665 Y33 T35 K129 R131 N132 R146 K147 R181 R274
BS02 dna O R421 R430 Q571 R30 R39 Q180
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:2o93, PDBe:2o93, PDBj:2o93
PDBsum2o93
PubMed18462673
UniProtQ13469|NFAC2_HUMAN Nuclear factor of activated T-cells, cytoplasmic 2 (Gene Name=NFATC2)

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