Structure of PDB 2ga6 Chain O

Receptor sequence

>2ga6O (length=118)

ANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVT
PEANMDQESFGGASCCLYCRCHIDHPNFCDLKGKYVQIPTTCANDPVGFT
LRNTVCTVCGMWKGYGCS

3D structure

• PDB: 2ga6 Dodecamer Structure of Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein nsp10
• Chain: O
• Resolution: 2.7 Å

Enzymatic activity

• Enzyme Commision number: 2.7.7.50: mRNA guanylyltransferase.
  3.4.19.12: ubiquitinyl hydrolase 1.
  3.4.22.-
  3.4.22.69: SARS coronavirus main proteinase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ZN	O	H83 C90	H75 C79

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0008270 zinc ion binding

Biological Process

• GO:0019079 viral genome replication

External links

• PDB: RCSB:2ga6, PDBe:2ga6, PDBj:2ga6
• PDBsum: 2ga6
• PubMed: 16873247
• UniProt: P0C6U8|R1A_SARS Replicase polyprotein 1a (Gene Name=1a)