Structure of PDB 2a69 Chain O

Receptor sequence
>2a69O (length=95) Species: 274 (Thermus thermophilus) [Search protein sequence]
AEPGIDKLFGMVDSKYRLTVVVAKRAQQLLRHGFKNTVLEPEERPKMQTL
EGLFDDPNAETWAMKELLTGRLVFGENLVPEDRLQKEMERIYPGE
3D structure
PDB2a69 Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins.
ChainO
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG O G34 P94 G95 G33 P93 G94
BS02 MG O A2 E3 A1 E2
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2a69, PDBe:2a69, PDBj:2a69
PDBsum2a69
PubMed16096056
UniProtQ8RQE7|RPOZ_THET8 DNA-directed RNA polymerase subunit omega (Gene Name=rpoZ)

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