Structure of PDB 1iru Chain O

Receptor sequence
>1iruO (length=244) Species: 9913 (Bos taurus) [Search protein sequence]
SRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIV
TQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANW
KYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQV
YKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITC
LSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAER
3D structure
PDB1iru The structure of the mammalian 20S proteasome at 2.75 A resolution.
ChainO
Resolution2.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG O T14 N128 A129 M131 T13 N127 A128 M130
Gene Ontology
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051603 proteolysis involved in protein catabolic process
Cellular Component
GO:0000502 proteasome complex
GO:0000932 P-body
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005839 proteasome core complex
GO:0019773 proteasome core complex, alpha-subunit complex

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Biological Process

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Cellular Component
External links
PDB RCSB:1iru, PDBe:1iru, PDBj:1iru
PDBsum1iru
PubMed12015144
UniProtQ2YDE4|PSA6_BOVIN Proteasome subunit alpha type-6 (Gene Name=PSMA6)

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