Structure of PDB 8fl3 Chain NU

Receptor sequence
>8fl3NU (length=833) Species: 9606 (Homo sapiens) [Search protein sequence]
QHDFQKVKLKVGKKKPKLQNATPTNFKTKTIHLPEQLKEDGTLPTNNRKL
NIKDLLSQMHHYNAGVKQSALLGLKDLLSQYPFIIDAHLSNILSEVTAVF
TDKDANVRLAAVQLLQFLAPKIRAEQISPFFPLVSAHLSSAMTHITEGIQ
EDSLKVLDILLEQYPALITGRSSILLKNFVELISHQQLSQSWILSVNPNR
RLTSQQWRLKVLVRLSKFLQALADGSSRLNSIFINWKEHANDQQHIQVYE
NGGSQPNVSSQFRLRGLSSTENLKGFIEIIIPLLIECWVEAVPGIEREPL
QVMQQVLNIISLLWKLSKQQDETHKLESWLRKNYLIDFKHHFMSRFPYVL
NNIDHLLLNLTLSDIMVSLANASTLQKDCSWIEMIRKFVTETLEDGSRLN
SKQLNRLLGVSWRLMQIQPNREDTETLIKAVYTLYQQRGLILPVRTLLLK
FFSKIYQTYRSKVLSRWLAGLPLQLAHLGSRNPELSTQLIDIIHTAAARA
NKELLKSLQATALRIYDPQEGAVVVLPADSQQRLVQLVYFLPSLPADLLS
RLSRCCIMGRLSSSLAAMLIGILHMRSSFSGWKYSAKDWLMSDVDYFSFL
FSTLTGFSKEELTWLQSLRGVPHVIQTQLSPVLLYLTDLDQFLHHWDVTE
AVFHSLLVIPARSQNFDILQSAISKHLVGLTVIPDSTAGCVFGVICKLLD
HTCVVSETLLPFLASCCYSLLYFLLTIEKGEAEHLRKRDKLWGVCVSILA
LLPRVLRLMLQSLRVNRVGPEELPVVGQLLRLLLQHAPLRTHMLTNAILV
QQIIKNITTLKSGSVQEQWLTDLHYCFNVYITG
3D structure
PDB8fl3 Principles of human pre-60 S biogenesis.
ChainNU
Resolution2.53 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide NU S634 F663 Y668 D677 V678 S682 F685 S686 Q748 D751 I752 S755 H760 S550 F579 Y584 D593 V594 S598 F601 S602 Q664 D667 I668 S671 H676
BS02 rna NU K13 K17 K22 N27 H39 N54 R55 K56 L57 S64 H68 Y69 K6 K10 K15 N20 H32 N47 R48 K49 L50 S57 H61 Y62
Gene Ontology
Molecular Function
GO:0005515 protein binding
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0071339 MLL1 complex

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Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:8fl3, PDBe:8fl3, PDBj:8fl3
PDBsum8fl3
PubMed37410842
UniProtQ9NXF1|TEX10_HUMAN Testis-expressed protein 10 (Gene Name=TEX10)

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