Structure of PDB 8fla Chain NR

Receptor sequence
>8flaNR (length=152) Species: 9606 (Homo sapiens) [Search protein sequence]
KVIHPYSRKAAQITREAHKQEKKEKLKNEKALRLNLVGEKLQWFQNHLDP
QKKRYSKKDACELIERYLNRFSSELEQIELHNSIRDRQGRRHCSRETVIK
QTMERERQQFEGYGLEIPDILNASNLKTFREWDFDLKKLPNIKMRKICAN
DA
3D structure
PDB8fla Principles of human pre-60 S biogenesis.
ChainNR
Resolution2.63 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna NR H18 S21 R22 K23 R29 K33 K37 D100 R101 Q102 R105 S108 H4 S7 R8 K9 R15 K19 K23 D86 R87 Q88 R91 S94
BS02 rna NR R29 K36 K151 P154 N155 R15 K22 K137 P140 N141
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:1990275 preribosome binding
Biological Process
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus

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Cellular Component
External links
PDB RCSB:8fla, PDBe:8fla, PDBj:8fla
PDBsum8fla
PubMed37410842
UniProtQ96EY4|TMA16_HUMAN Translation machinery-associated protein 16 (Gene Name=TMA16)

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