Structure of PDB 8cku Chain NN

Receptor sequence

>8ckuNN (length=169) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]

QNPMRDLKIEKLVLNISVGESGDRLTRASKVLEQLSGQTPVQSKARYTVR
TFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLRDRNFSATGNFGFG
IDEHIDLGIKYDPSIGIFGMDFYVVMNRPGARVTRRKRCKGTVGNSHKTT
KEDTVSWFKQKYDADVLDK

3D structure

PDB

8cku mRNA reading frame maintenance during eukaryotic ribosome translocation

Chain

Resolution

3.11 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	NN	K16 N20 S22 S48 R51 Y52 T56 F57 H68 R94 N95 S97 A98 T99 G103 F104 G105 D107 G124 D126 Y128 R140 K142	K11 N15 S17 S43 R46 Y47 T51 F52 H63 R89 N90 S92 A93 T94 G98 F99 G100 D102 G119 D121 Y123 R135 K137
BS02	rna	NN	P8 M9 T44 V46 T70 R72 G135 R137 R140 R141 R143 G149 N150 H152	P3 M4 T39 V41 T65 R67 G130 R132 R135 R136 R138 G144 N145 H147

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:8cku, PDBe:8cku, PDBj:8cku
PDBsum	8cku
PubMed	38030725
UniProt	P0C0W9\|RL11A_YEAST Large ribosomal subunit protein uL5A (Gene Name=RPL11A)

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