Structure of PDB 8cg8 Chain NN

Receptor sequence

>8cg8NN (length=169) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]

QNPMRDLKIEKLVLNISVGESGDRLTRASKVLEQLSGQTPVQSKARYTVR
TFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLRDRNFSATGNFGFG
IDEHIDLGIKYDPSIGIFGMDFYVVMNRPGARVTRRKRCKGTVGNSHKTT
KEDTVSWFKQKYDADVLDK

3D structure

PDB

8cg8 Cryo-EM analysis of eukaryotic ribosome translocation intermediates

Chain

Resolution

2.57 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	NN	K16 V18 N20 S22 G24 S48 A50 R51 F57 A66 H68 R94 N95 S97 A98 T99 N101 F104 G105 D107 G124 D126 Y128 K142	K11 V13 N15 S17 G19 S43 A45 R46 F52 A61 H63 R89 N90 S92 A93 T94 N96 F99 G100 D102 G119 D121 Y123 K137
BS02	rna	NN	P8 M9 R10 Q43 T44 V46 H68 T70 R72 G135 R137 V138 R141 R143 V148 G149 N150 H152	P3 M4 R5 Q38 T39 V41 H63 T65 R67 G130 R132 V133 R136 R138 V143 G144 N145 H147

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:8cg8, PDBe:8cg8, PDBj:8cg8
PDBsum	8cg8
PubMed	38030725
UniProt	P0C0W9\|RL11A_YEAST Large ribosomal subunit protein uL5A (Gene Name=RPL11A)

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