Structure of PDB 8fku Chain NH

Receptor sequence
>8fkuNH (length=180) Species: 9606 (Homo sapiens) [Search protein sequence]
MRPLTEEETRVMFEKIAKYIGENLQLLVDRPDGTYCFRLHNDRVYYVSEK
IMKLAANISGDKLVSLGTCFGKFTKTHKFRLHVTALDYLAPYAKYKVWIK
PGAEQSFLYGNHVLKSGLGRITENTSQYQGVVVYSMADIPLGFGVAAKST
QDCRKVDPMAIVVFHQADIGEYVRHEETLT
3D structure
PDB8fku Principles of human pre-60 S biogenesis.
ChainNH
Resolution2.82 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna NH M1 K15 H40 N41 A56 N57 K72 T74 R80 L81 Y128 F164 Q166 M1 K15 H40 N41 A56 N57 K72 T74 R80 L81 Y128 F164 Q166
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0042254 ribosome biogenesis
GO:0042255 ribosome assembly
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0030687 preribosome, large subunit precursor

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Molecular Function
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Cellular Component
External links
PDB RCSB:8fku, PDBe:8fku, PDBj:8fku
PDBsum8fku
PubMed37410842
UniProtQ9Y221|NIP7_HUMAN 60S ribosome subunit biogenesis protein NIP7 homolog (Gene Name=NIP7)

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