Structure of PDB 7mq8 Chain NH

Receptor sequence
>7mq8NH (length=1066) Species: 9606 (Homo sapiens) [Search protein sequence]
EILFHSSLLRLQVEELLKEVRLSEKKKDRIDAFLREVNQRVVRVPSVPET
ELTDQAWLPAGVRVPLHQVPYAVKGCFRFLPPAQVTVVGSYLLGTCIRPD
INVDVALTMPREILQDKDGLNQRYFRKRALYLAHLAHHLAQDPLFGSVCF
SYTNGCHLKPSLLLRPRGKDERLVTVRLHPCPPPDFFRPCRLLPTKNNVR
SAWYRGQSPAGDGSPEPPTPRYNTWVLQDTVLESHLQLLSTILSSAQGLK
DGVALLKVWLRQRELDKGQGGFTGFLVSMLVVFLVSTRKIHTTMSGYQVL
RSVLQFLATTDLTVNGISLCLSSDPSLPALADFHQAFSVVFLDSSGHLNL
CADVTASTYHQVQHEARLSMMLLDSRADDGFHLLLMTPKPMIRAFDHVLH
LRPLSRLQAACHRLKLWPELQDNGGDYVSAALGPLTTLLEQGLGARLNLL
AHSRPPVPEWDISQDPPKHKDSGTLTLGLLLRPEGLTSVLELGPEADQPE
AAKFRQFWGSRSELRRFQDGAIREAVVWEAASMSQKRLIPHQVVTHLLAL
HADIPETCVHYVGGPLDALIQGLKETSSTGEEALVAAVRCYDDLSRLLWG
LEGLPLTVSAVQGAHPVLRYTEVFPPTPVRPAFSFYETLRERSSLLPRLD
KPCPAYVEPMTVVCHLEGSGQWPQDAEAVQRVRAAFQLRLAELLTQQHGL
QCRATATHTDVLKDGFVFRIRVAYQREPQILKEVQSPEGMISLRDTAASL
RLERDTRQLPLLTSALHGLQQQHPAFSGVARLAKRWVRAQLLGEGFADES
LDLVAAALFLHPEPFTPPSSPQVGFLRFLFLVSTFDWKNNPLFVNLNNEL
TVEEQVEIRSGFLAARAQLPVMVIVTPQDRKNSVWTQDGPSAQILQQLVV
LAAEALPMLEKQLMDPRGPGDIRTVFRPPLDIYDVLIRLSPRHIPRHRQA
VDSPAASFCRGLLSQPGPSSLMPVLGYDPPQLYLTQLREAFGDLALFFYD
QHGGEVIGVLWKPTSFQPQPFKASSTKGRMVMSRGGELVMVPNVEAILED
FAVLGEGLVQTVEARS
3D structure
PDB7mq8 Nucleolar maturation of the human small subunit processome.
ChainNH
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna NH K149 R186 L189 Q190 K192 C265 R266 K271 R275 R801 Q804 K74 R111 L114 Q115 K117 C190 R191 K196 R200 R726 Q729
BS02 ATP NH S165 N177 D179 R252 Q303 F350 L425 S90 N102 D104 R177 Q228 F275 L350
BS03 MG NH N177 D179 R252 N102 D104 R177
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0006364 rRNA processing
GO:0006409 tRNA export from nucleus
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0000794 condensed nuclear chromosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0032040 small-subunit processome
GO:0032545 CURI complex
GO:0034456 UTP-C complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7mq8, PDBe:7mq8, PDBj:7mq8
PDBsum7mq8
PubMed34516797
UniProtQ9H6R4|NOL6_HUMAN Nucleolar protein 6 (Gene Name=NOL6)

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