Structure of PDB 5tgm Chain N5

Receptor sequence

>5tgmN5 (length=121) Species: 4932 (Saccharomyces cerevisiae)

KALKVRTSATFRLPKTLKLARAPKYASKAVPHYNRLDSYKVIEQPITSET
AMKKVEDGNILVFQVSMKANKYQIKKAVKELYEVDVLKVNTLVRPNGTKK
AYVRLTADYDALDIANRIGYI

3D structure

• PDB: 5tgm Molecular insights into protein synthesis with proline residues.
• Chain: N5
• Resolution: 3.5 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	N5	A30 T31 R33 L34 P35 K36 K39 L40 R42 A43 K45 Y46 S69 T71 K75 N91 K92 Y93 N111 T112 K120 Y123 R125	A9 T10 R12 L13 P14 K15 K18 L19 R21 A22 K24 Y25 S48 T50 K54 N70 K71 Y72 N90 T91 K99 Y102 R104
BS02	rna	N5	L24 R27 T37 L38 R42 S48 K49 P52 H53 Y54 N55 R56 K61 M88 K89 Y93 Q94	L3 R6 T16 L17 R21 S27 K28 P31 H32 Y33 N34 R35 K40 M67 K68 Y72 Q73
BS03	MG	N5	H53 Y54	H32 Y33

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome

External links

• PDB: RCSB:5tgm, PDBe:5tgm, PDBj:5tgm
• PDBsum: 5tgm
• PubMed: 27827794
• UniProt: P04456|RL25_YEAST Large ribosomal subunit protein uL23 (Gene Name=RPL25)