Structure of PDB 8w7e Chain N

Receptor sequence
>8w7eN (length=171) Species: 9606 (Homo sapiens) [Search protein sequence]
LIPIVVYDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSENKKPIHM
YINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPGMR
HSLPNSRIMIHQPIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERD
RYMSPMEAQEFGILDKVLVHP
3D structure
PDB8w7e Design, synthesis and biological evaluations of novel small molecular hyper-activators of human caseinolytic peptidase P (hClpP)
ChainN
Resolution2.8 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 9I3 N L104 S108 Y138 L38 S42 Y71
BS02 9I3 N R78 L79 E82 H116 Y118 W146 V148 R12 L13 E16 H49 Y51 W79 V81
External links
PDB RCSB:8w7e, PDBe:8w7e, PDBj:8w7e
PDBsum8w7e
PubMed
UniProtQ16740|CLPP_HUMAN ATP-dependent Clp protease proteolytic subunit, mitochondrial (Gene Name=CLPP)

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