Structure of PDB 8uk9 Chain N

Receptor sequence
>8uk9N (length=305) Species: 10665 (Tequatrovirus T4) [Search protein sequence]
ITVNEKEHILEQKYRPSTIDECILPAFDKETFKSITSKGKIPHIILHSPS
PGTGKTTVAKALCHDVNADMMFVNGSDCKIDFVRGPLTNFASAASFDGRQ
KVIVIDEFCRSGLAESQRHLRSFMEAYSSNCSIIITANNIDGIIKPLQSR
CRVITFGQPTDEDKIEMMKQMIRRLTEICKHEGIAIADMKVVAALVKKNF
PDFRKTIGELDSYSSKGVLAIDDVLESLKNKDVKQLRALAPKYAADYSWF
VGKLAEEIYSRVTPQSIIRMYEIVGENNQYHGIAANTELHLAYLFIQLAC
EMQWK
3D structure
PDB8uk9 Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM
ChainN
Resolution3.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna N K80 I81 R85 K79 I80 R84
BS02 ADP N E12 R16 P17 I24 G53 T54 G55 K56 T57 T58 F204 R205 E11 R15 P16 I23 G52 T53 G54 K55 T56 T57 F203 R204
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006281 DNA repair
GO:0039686 bidirectional double-stranded viral DNA replication
GO:0039693 viral DNA genome replication
Cellular Component
GO:0005663 DNA replication factor C complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8uk9, PDBe:8uk9, PDBj:8uk9
PDBsum8uk9
PubMed38177685
UniProtP04526|LOADL_BPT4 Sliding-clamp-loader large subunit (Gene Name=44)

[Back to BioLiP]