Structure of PDB 8ovc Chain N

Receptor sequence

>8ovcN (length=535) Species: 1772 (Mycolicibacterium smegmatis)

DFAKLAAAQGDAIDSRYHPSAAVRRQLNKVFPTHWSFLLGEIALYSFIIL
LLTGVWLTLFFDPSMAHVTYDGVYQPLRGVQMSRAYETALDISFEVRGGL
FVRQVHHWAALMFAASIMVHLARIFFTGAFRRPREANWVIGSLLLILAMF
EGFFGYSLPDDLLSGTGIRAALSGITMGIPVIGTWMHWALFGGDFPGEIL
IPRLYALHILLIPGIILALIGAHLALVWFQKHTQFPGPGRTETNVVGVRV
MPVFAVKSGAFFAMITGVLGLMGGLLTINPIWNLGPYKPSQVSAGSQPDF
YMMWTDGLIRLWPAWEFYPFGHTIPQGVWVAVGMGLVFALLIAYPFIEKK
VTGDDAHHNLLQRPRDVPVRTAIGSMAIALYLLLTFACMNDIIALKFHIS
LNATTWIGRIGMVVLPAIVYFVAYRWAISLQRSDREVLEHGVETGIIKRL
PHGAYVELHQPLGPVDEHGHPIPLEYAGAPLPKRMNKLGSGGAPGTGSFL
FPDPAVEHEALTEAAHASEHKSLTALKEHQDRIHG

3D structure

• PDB: 8ovc Long-range charge transfer mechanism of the III 2 IV 2 mycobacterial supercomplex.
• Chain: N
• Resolution: 2.8 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MQ9	N	M121 V340 A380	M118 V337 A377
BS02	MQ9	N	N393 F400	N390 F397
BS03	HEM	N	F50 L53 G57 L60 H109 H110 A113 E154 G158 Y159 H211 N282	F47 L50 G54 L57 H106 H107 A110 E151 G155 Y156 H208 N279
BS04	MQ9	N	E44 L47 A221	E41 L44 A218
BS05	MQ9	N	V142 L175 I178 A342	V139 L172 I175 A339
BS06	HEM	N	F40 G43 H123 R126 I127 W141 G144 H226 H235 T236	F37 G40 H120 R123 I124 W138 G141 H223 H232 T233
BS07	9YF	N	W409 I410	W406 I407

Gene Ontology

Molecular Function

• GO:0008121 ubiquinol-cytochrome-c reductase activity

Biological Process

• GO:1902600 proton transmembrane transport

Cellular Component

• GO:0016020 membrane

External links

• PDB: RCSB:8ovc, PDBe:8ovc, PDBj:8ovc
• PDBsum: 8ovc
• PubMed: 38902248
• UniProt: A0R052