Structure of PDB 8ifl Chain N

Receptor sequence
>8iflN (length=412) Species: 1393122 (Thermoflavifilum thermophilum) [Search protein sequence]
NKIFISHATPEDDDFTRWLSLKLIGLGYEVWCDILFLDFWSTIEKEIREN
TCKFLIVSSTAGNKREGVLKELAVATKVKKHLQDDMFIIPLAIDENLSYD
DINIEIVRLNAIDFKKSWAKGLQDLLDAFEKQNVPPPDHSKSNLLYQQIF
LHDKQAIEKEETYDSNWFPIISFPNELRFHRYDWRLPKQFDVRTLAFPAI
RYKEYLCTFAWEYDFIHQLPKTETYNGQESIRISTSDILSGRYDTDFIRN
YECQRLIVQLINKAFELRMKDKNVREYQMSKTFAYWIEKGKLEKDKFEKI
KLVGKQKNKYWHFGISAAGKLYPSPVLMVSSHIIFTMDGINLIKSKSIQH
SSRRKQGKNWWNDKWREKLLAFIRFLSDDQNAIYLNVGSEEKILISNKPL
KFFGKMSYVTPS
3D structure
PDB8ifl Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system.
ChainN
Resolution3.11 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna N K196 Y210 K211 E212 E260 R263 M287 S288 H340 K354 H358 R361 R362 K188 Y202 K203 E204 E252 R255 M279 S280 H332 K346 H350 R353 R354
BS02 dna N R201 V266 Q267 N270 H358 R362 K366 W369 R193 V258 Q259 N262 H350 R354 K358 W361
Gene Ontology
Biological Process
GO:0007165 signal transduction

View graph for
Biological Process
External links
PDB RCSB:8ifl, PDBe:8ifl, PDBj:8ifl
PDBsum8ifl
PubMed37932528
UniProtA0A1I7NFG5

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