Structure of PDB 8hgk Chain N

Receptor sequence
>8hgkN (length=180) Species: 9606 (Homo sapiens) [Search protein sequence]
LIPIVVEQTGRGERAYDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQ
SESNKKPIHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSL
LLAAGTPGMRHSLPNSRIMIHQPIQAEEIMKLKKQLYNIYAKHTKQSLQV
IESAMERDRYMSPMEAQEFGILDKVLVHPP
3D structure
PDB8hgk Crystal structure of human ClpP in complex with ZK53
ChainN
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.92: endopeptidase Clp.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZLL N F105 S108 Y138 F48 S51 Y81
BS02 ZLL N E82 Y118 W146 E25 Y61 W89
Gene Ontology
Molecular Function
GO:0004176 ATP-dependent peptidase activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:8hgk, PDBe:8hgk, PDBj:8hgk
PDBsum8hgk
PubMed37923710
UniProtQ16740|CLPP_HUMAN ATP-dependent Clp protease proteolytic subunit, mitochondrial (Gene Name=CLPP)

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