Structure of PDB 8gam Chain N

Receptor sequence
>8gamN (length=205) Species: 486 (Neisseria lactamica) [Search protein sequence]
RFILEISGDLACFTRSELKVERVSYPVITPSAARNILMAILWKPAIRWKV
LKIEILKPIQWTNIRRNEVGTKMSERSGSLYIEDNRQQRASMLLKDVAYR
IHADFDMTSEAGESDNYVKFAEMFKRRAKKGQYFHQPYLGCREFPCDFRL
LEKAEDGLPLEDITQDFGFMLYDMDFSKSDPRDSNNAEPMFYQCKAVNGV
ITVPP
3D structure
PDB8gam Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.
ChainN
Resolution3.46 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna N R23 N36 M39 W43 R67 N68 E69 V70 T72 K73 Q89 F135 Y139 G141 C142 R143 E144 F177 R183 R22 N35 M38 W42 R66 N67 E68 V69 T71 K72 Q88 F134 Y138 G140 C141 R142 E143 F176 R182
BS02 dna N E76 R77 R87 Q88 E75 R76 R86 Q87
BS03 dna N T72 K73 S75 R77 S78 D85 T71 K72 S74 R76 S77 D84
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:8gam, PDBe:8gam, PDBj:8gam
PDBsum8gam
PubMed38242128
UniProtD0W8X4

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