Structure of PDB 7ywx Chain N

Receptor sequence
>7ywxN (length=318) Species: 9606 (Homo sapiens) [Search protein sequence]
DETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQH
LIHLCEEKRASISDAALLDIIYMQFHQHQKVWEVFQMSKGPGEDVDLFDM
KQFKNSFKKILQRALKNVTVSFRETEENAVWIRIAWGTQYTKPNQYKPTY
VVYYSQTPYAFTSSSMLRRNTPLLGQALTIASKHHQIVKMDLRSRYLDSL
KAIVFKQYNQTFETHNMDSRIIHENIVEKERVQRITQETFGDYPQPQLEF
AQYKLETKFKSSILAEREEPLRCLIKFSSPHLLEALKSLAPAGIADAPLS
PLLTCIPNKRMNYFKIRD
3D structure
PDB7ywx Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
ChainN
Resolution12.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna N M18 R44 M17 R43
Gene Ontology
Biological Process
GO:0007059 chromosome segregation
GO:0034080 CENP-A containing chromatin assembly
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0000939 inner kinetochore
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005829 cytosol

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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7ywx, PDBe:7ywx, PDBj:7ywx
PDBsum7ywx
PubMed35420891
UniProtQ96H22|CENPN_HUMAN Centromere protein N (Gene Name=CENPN)

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