Structure of PDB 7xho Chain N

Receptor sequence
>7xhoN (length=305) Species: 9606 (Homo sapiens) [Search protein sequence]
MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQ
HLIHLCEEKRASISDAALLDIIYMQFHQHQKVWDVFQMSKGPGEDVDLFD
MKQFKNSFKKILQRALKNVTVSFRETEENAVWIRIAWGTQYTKPNQYKPT
YVVYYSQTPYAFTSSSMLRRNTPLLGQALTIASKHHQIVKMDLRSRYLDS
LKAIVFKQYNQDSRIIHENIVEKERVQRITQETFGDYPQPQLEFAQYKLE
TKFKEPLRCLIKFSSPHLLEALKSLAPAGIADAPLSPLLTCIPNKRMNYF
KIRDK
3D structure
PDB7xho Structural insights into human CCAN complex assembled onto DNA.
ChainN
Resolution3.29 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide N Q268 Y269 K270 L271 E272 L322 F334 K335 I336 R337 D338 K339 Q246 Y247 K248 L249 E250 L288 F300 K301 I302 R303 D304 K305
Gene Ontology
Biological Process
GO:0007059 chromosome segregation
GO:0034080 CENP-A containing chromatin assembly
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0000939 inner kinetochore
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005829 cytosol

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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7xho, PDBe:7xho, PDBj:7xho
PDBsum7xho
PubMed36085283
UniProtQ96H22|CENPN_HUMAN Centromere protein N (Gene Name=CENPN)

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