Structure of PDB 7xhn Chain N

Receptor sequence
>7xhnN (length=305) Species: 9606 (Homo sapiens) [Search protein sequence]
MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQ
HLIHLCEEKRASISDAALLDIIYMQFHQHQKVWEVFQMSKGPGEDVDLFD
MKQFKNSFKKILQRALKNVTVSFRETEENAVWIRIAWGTQYTKPNQYKPT
YVVYYSQTPYAFTSSSMLRRNTPLLGQALTIASKHHQIVKMDLRSRYLDS
LKAIVFKQYNQDSRIIHENIVEKERVQRITQETFGDYPQPQLEFAQYKLE
TKFKEPLRCLIKFSSPHLLEALKSLAPAGIADAPLSPLLTCIPNKRMNYF
KIRDK
3D structure
PDB7xhn Structural insights into human CCAN complex assembled onto DNA.
ChainN
Resolution3.71 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna N K148 S166 K148 S166
BS02 dna N K45 M167 R169 R170 K45 M167 R169 R170
BS03 peptide N L322 I336 R337 L288 I302 R303
Gene Ontology
Biological Process
GO:0007059 chromosome segregation
GO:0034080 CENP-A containing chromatin assembly
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0000939 inner kinetochore
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005829 cytosol

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Biological Process
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Cellular Component
External links
PDB RCSB:7xhn, PDBe:7xhn, PDBj:7xhn
PDBsum7xhn
PubMed36085283
UniProtQ96H22|CENPN_HUMAN Centromere protein N (Gene Name=CENPN)

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