Structure of PDB 7vpx Chain N

Receptor sequence
>7vpxN (length=50) Species: 9606 (Homo sapiens) [Search protein sequence]
PKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVKDYYQKWMEEQAQSLID
3D structure
PDB7vpx Mechanism for Branch Site Recognition and Proofreading During Prespliceosome Assembly
ChainN
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna N T11 Y12 T14 H24 R28 T10 Y11 T13 H23 R27
BS02 rna N P2 K3 H15 S17 S19 V20 K29 P1 K2 H14 S16 S18 V19 K28
BS03 ZN N C6 H24 H30 C5 H23 H29
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003727 single-stranded RNA binding
GO:0003729 mRNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0030619 U1 snRNA binding
GO:0030627 pre-mRNA 5'-splice site binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0000387 spliceosomal snRNP assembly
GO:0000395 mRNA 5'-splice site recognition
GO:0000398 mRNA splicing, via spliceosome
Cellular Component
GO:0000243 commitment complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0005685 U1 snRNP
GO:0015030 Cajal body
GO:0071004 U2-type prespliceosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:7vpx, PDBe:7vpx, PDBj:7vpx
PDBsum7vpx
PubMed38196034
UniProtP09234|RU1C_HUMAN U1 small nuclear ribonucleoprotein C (Gene Name=SNRPC)

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