Structure of PDB 7u32 Chain N

Receptor sequence
>7u32N (length=261) Species: 36374 (Visna/maedi virus EV1 KV1772) [Search protein sequence]
NIPLAEEEHNKWHQDAVSLHLEFGIPRTAAEDIVQQCDVCQENKIDHWQV
DYTHYEDKIILVWVETNSGLIYAERVKGETGQEFRVQTMKWYAMFAPKSL
QSDNGPAFVAESTQLLMKYLGIEHTTGIPWNPQSQALVERTHQTLKNTLE
KLIPMFNAFESALAGTLITLNIKRKGGLGTSPMDIFIFNKEQQRIQQQSK
SKQEKIRFCYYRTRKRGHPGEWQGPTQVLWGGDGAIVVKDRGTDRYLVIA
NKDVKFIPPPK
3D structure
PDB7u32 Multivalent interactions essential for lentiviral integrase function.
ChainN
Resolution3.46 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.4: ribonuclease H.
3.4.23.-
3.6.1.23: dUTP diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna N W245 G249 W230 G234
BS02 ZN N H12 H16 C40 H9 H13 C37
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:7u32, PDBe:7u32, PDBj:7u32
PDBsum7u32
PubMed35504909
UniProtP35956|POL_VILVK Gag-Pol polyprotein (Gene Name=pol)

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