Structure of PDB 7qws Chain N

Receptor sequence

>7qwsN (length=203) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

GAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRL
GYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSV
AEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWI
TKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLH
RYR

3D structure

PDB

7qws Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting.

Chain

Resolution

3.4 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	N	G2 Y4 K5 Q8 R12 K13 K14 Q15 R24 W28 R31 Q32 S34 A35 H37 P40 R41 R44 K47 R49 R50 L51 K54 A55 Q57 R65 R67 R68 G69 G70 R71 K72 R73 P74 K77 T80 Y81 G82 K83 P84 V85 H86 H87 V89 N90 Q91 K93 F94 A95 R96 S97 E104 R105 R108 A112 D124 S125 Y127 F138 A141 R144 W150 P154 V155 H156 K157 H158 M161 R162 L164 S166 R169 K170 S171 R172 G173 L174 K176 G177 H178 K179 F180 H181 H182 I184 G185 G186 S187 W192 R193 R195 Q199 H201 R202 R204	G1 Y3 K4 Q7 R11 K12 K13 Q14 R23 W27 R30 Q31 S33 A34 H36 P39 R40 R43 K46 R48 R49 L50 K53 A54 Q56 R64 R66 R67 G68 G69 R70 K71 R72 P73 K76 T79 Y80 G81 K82 P83 V84 H85 H86 V88 N89 Q90 K92 F93 A94 R95 S96 E103 R104 R107 A111 D123 S124 Y126 F137 A140 R143 W149 P153 V154 H155 K156 H157 M160 R161 L163 S165 R168 K169 S170 R171 G172 L173 K175 G176 H177 K178 F179 H180 H181 I183 G184 G185 S186 W191 R192 R194 Q198 H200 R201 R203
BS02	rna	N	R38 Q57 Y62 H109 C110 D136 H139	R37 Q56 Y61 H108 C109 D135 H138

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:0022626	cytosolic ribosome
GO:0044391	ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:7qws, PDBe:7qws, PDBj:7qws
PDBsum	7qws
PubMed	35201867
UniProt	G1T0C1\|RL15_RABIT Large ribosomal subunit protein eL15 (Gene Name=RPL15)

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