Structure of PDB 7qoo Chain N

Receptor sequence
>7qooN (length=320) Species: 9606 (Homo sapiens) [Search protein sequence]
MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQ
HLIHLCEEKRASISDAALLDIIYMQFHQHQKVWEVFQMSKGPGEDVDLFD
MKQFKNSFKKILQRALKNVTVSFRETEENAVWIRIAWGTQYTKPNQYKPT
YVVYYSQTPYAFTSSSMLRRNTPLLGQALTIASKHHQIVKMDLRSRYLDS
LKAIVFKQYNQTFEDSRIIHENIVEKERVQRITQETFGDYPQPQLEFAQY
KLETKFKSGLNGSILAEREEPLRCLIKFSSPHLLEALKSLAPAGIADAPL
SPLLTCIPNKRMNYFKIRDK
3D structure
PDB7qoo Structure of the human inner kinetochore CCAN complex and its significance for human centromere organization.
ChainN
Resolution4.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide N F334 K335 F315 K316
Gene Ontology
Biological Process
GO:0007059 chromosome segregation
GO:0034080 CENP-A containing chromatin assembly
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0000939 inner kinetochore
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005829 cytosol

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Biological Process

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Cellular Component
External links
PDB RCSB:7qoo, PDBe:7qoo, PDBj:7qoo
PDBsum7qoo
PubMed35525244
UniProtQ96H22|CENPN_HUMAN Centromere protein N (Gene Name=CENPN)

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