Structure of PDB 7mbn Chain N

Receptor sequence
>7mbnN (length=93) Species: 8355 (Xenopus laevis) [Search protein sequence]
TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLA
HYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA
3D structure
PDB7mbn Regulation of MLL1 Methyltransferase Activity in Two Distinct Nucleosome Binding Modes.
ChainN
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna N T29 R30 Y39 G50 I51 S52 S53 R83 S84 T85 T1 R2 Y11 G22 I23 S24 S25 R55 S56 T57
BS02 dna N K31 I36 Y37 K3 I8 Y9
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:7mbn, PDBe:7mbn, PDBj:7mbn
PDBsum7mbn
PubMed34928138
UniProtP02281|H2B11_XENLA Histone H2B 1.1

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