Structure of PDB 7aod Chain N

Receptor sequence
>7aodN (length=1156) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence]
MSFQTLERERTFKNPPKDGTSFPDLQKAVKPHVDSFNALTNAGLLNYAVK
EIGEKCAFDSITQEEGGALKFGNKISFRVDEVQIAKPMLSSRERSSINRK
VYPAEARERLTTYKSRLVLKFSWSVNGGPRQSEMREVGMIPIMVRSNRCH
LEGLSPAELIAHKEESEEMGGYFIVNGIEKLIRMLILPKRNHPTAIIRPS
FANRGTSYSQYGLSIRCVRPDQSSLTNTLHYLNNGVTMFRFHWRKNEYLI
PSMMILKALLETSDKEIFEGIVGKDLGNTFLTDRVELMLRAYKSYGLYSQ
TETLQYLGSKFRVVLGVAEDLTDVEVGRFLLQKVVLVHLREAKDKFRLLL
FMIRKLYALVAGECCADNPDSPQHQEILLGGFLYGQILKEKIEDWLNSIR
AQINLDVRRSAPGVDFSDRKYLTRVFSKINNDIGTKLQYFLSTGNLVSNT
GLDLQQATGYTVVAEKLNFYRFLSHFRMVHRGAFFAELKTTTVRKLLPEA
WGFMCPVHTPDGSPCGLLNHLARKCEIVTHPSDVSQIPSLLLSLGVDPPS
VVGHESGWGCVQLDGKIVGWCTYKLAKHVADVLRLMKIEYAVKLRNGTAT
EPAKVPLDLEIGYVPPSHNGQYPGLYLFSNPARMVRPVKHISTGELDMLG
PFEQVYMDIACFPKEIVPKVSTHVEYSPTNVLSIVANMTPFSDFNQSPRN
MYQCQMGKQTMGTPGTALRYRTDNKLYRLQTGQTPVVRPKLHNTYGLDHY
PNGTNAVVAVISYTGYDMEDAMILNKSAHERGFGYGTVYKGESFDLSQKR
RRGEPVVHHFGFAPGSTPRREWLQKLDADGLPFIGIKLEDGDPIVAYYDE
STGQNFIETYHGTEPGFVDEVRLLGNDVGDSECQQIHVKLRITRSPIIGD
KFSSRHGQKGICSQKWPTVDMPFTESGMQPDIIINPHAFPSRMTIGMFIE
SLAGKAGACHGLAQDSTPFIYSEQQTAADYFGEQLVKAGYNYHGNEPMYS
GITGQEMKADIYIGVVYYQRLRHMFQVRTTGPIHNLTRQPVKIRFGEMER
DAVIGHGTSFLMQDRLMNCSDYAQSWVCRDCGSIISIMSTISMNGVGSAS
EVRCRSCAKTSDIWQDGSGKKFVGGTNTTLIALPSVFNYLTAELTAMNIK
MMLEVK
3D structure
PDB7aod Conserved strategies of RNA polymerase I hibernation and activation.
ChainN
Resolution4.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN N C1089 C1092 C1115 C1118 C1078 C1081 C1104 C1107
Gene Ontology
Molecular Function
GO:0001054 RNA polymerase I activity
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0006362 transcription elongation by RNA polymerase I
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005736 RNA polymerase I complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7aod, PDBe:7aod, PDBj:7aod
PDBsum7aod
PubMed33536435
UniProtQ9P7X8|RPA2_SCHPO Probable DNA-directed RNA polymerase I subunit RPA2 (Gene Name=rpa2)

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