Structure of PDB 7abf Chain N

Receptor sequence

>7abfN (length=56) Species: 9606 (Homo sapiens)

GYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSTLDQVKKRFEV
NKKKME

3D structure

• PDB: 7abf Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
• Chain: N
• Resolution: 3.9 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	N	K90 N94	K12 N16
BS02	rna	N	D97 H98 G101	D19 H20 G23

Gene Ontology

Molecular Function

• GO:0003676 nucleic acid binding
• GO:0003677 DNA binding
• GO:0005515 protein binding
• GO:0008270 zinc ion binding
• GO:0046872 metal ion binding

Biological Process

• GO:0000398 mRNA splicing, via spliceosome
• GO:0006397 mRNA processing
• GO:0008380 RNA splicing

Cellular Component

• GO:0005634 nucleus
• GO:0005654 nucleoplasm
• GO:0005681 spliceosomal complex
• GO:0046540 U4/U6 x U5 tri-snRNP complex
• GO:0071005 U2-type precatalytic spliceosome

External links

• PDB: RCSB:7abf, PDBe:7abf, PDBj:7abf
• PDBsum: 7abf
• PubMed: 33243851
• UniProt: Q96NC0|ZMAT2_HUMAN Zinc finger matrin-type protein 2 (Gene Name=ZMAT2)