Structure of PDB 6zkm Chain N

Receptor sequence
>6zkmN (length=347) Species: 9940 (Ovis aries) [Search protein sequence]
MNPIILIIILMTVMLGTIIVMISTHWLLIWIGFEMNMLAIIPIMMKKHNP
RATEASTKYFLTQSTASMLLMMAIIINLMFSGQWTVMKLFNPMASMLMTM
ALAMKLGMAPFHFWVPEVTQGIPLSSGLILLTWQKLAPMSVLYQILPSIN
LDLILTLSILSITIGGWGGLNQTQLRKIMAYSSIAHMGWMTAVLLYNPTM
TLLNLIIYIIMTSTMFTLFMANSTTTTLSLSHTWNKAPIMTILVLITLLS
MGGLPPLSGFMPKWMIIQEMTKNDSIILPTLMAITALLNLYFYMRLTYST
ALTMFPSTNNMKMKWQFPTTKRMTLLPTMTVLSTMLLPLTPILSILE
3D structure
PDB6zkm The coupling mechanism of mammalian respiratory complex I.
ChainN
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide N L151 D152 L155 L195 Y196 N273 L278 L151 D152 L155 L195 Y196 N273 L278
BS02 970 N M294 R295 Y298 M294 R295 Y298
Gene Ontology
Molecular Function
GO:0008137 NADH dehydrogenase (ubiquinone) activity
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0032981 mitochondrial respiratory chain complex I assembly
GO:0072593 reactive oxygen species metabolic process
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0045271 respiratory chain complex I

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6zkm, PDBe:6zkm, PDBj:6zkm
PDBsum6zkm
PubMed32972993
UniProtO78748|NU2M_SHEEP NADH-ubiquinone oxidoreductase chain 2 (Gene Name=MT-ND2)

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