Structure of PDB 6nud Chain N

Receptor sequence
>6nudN (length=212) Species: 1308 (Streptococcus thermophilus) [Search protein sequence]
TFAKIKFSAQIRLETGLHIGGSDAFAAIGAIASPVIKDPITNIPIIPGSS
LKGKMRTLLAKVYNEKVAEKPSDDSDILSRLFGNSKDKRFKMGRLIFRDA
FLSNADELDSLGVRSYTEVKFENTIDRITAEANPRQIERAIRNSTFDFEL
IYEITDENENQVEEDFKVIRDGLKLLELDYLGGSGSRGYGKVAFEKLKAT
TVFGNYDVKTLN
3D structure
PDB6nud Coupling of ssRNA cleavage with DNase activity in type III-A CRISPR-Csm revealed by cryo-EM and biochemistry.
ChainN
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna N G21 G54 K55 R57 S73 G84 S86 K92 M93 F122 E123 N124 T125 I126 E132 R136 Y181 G183 G184 S185 S187 G20 G53 K54 R56 S72 G83 S85 K91 M92 F121 E122 N123 T124 I125 E131 R135 Y180 G182 G183 S184 S186
BS02 rna N N134 P135 N133 P134
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:6nud, PDBe:6nud, PDBj:6nud
PDBsum6nud
PubMed30814678
UniProtA0A0A7HIF0|CSM3_STRTR CRISPR system Cms endoribonuclease Csm3 (Gene Name=csm3)

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