Structure of PDB 6h23 Chain N

Receptor sequence
>6h23N (length=168) Species: 9606 (Homo sapiens) [Search protein sequence]
YDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKPIHMAINSP
GGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTPGMRHSLPN
SRIMIHQPSIAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAMERDRYMS
PMEAQEFGILDKVLVHPP
3D structure
PDB6h23 Selective Activation of Human Caseinolytic Protease P (ClpP).
ChainN
Resolution3.089 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.92: endopeptidase Clp.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FJT N L104 F105 S108 Y138 L32 F33 S36 Y66
BS02 FJT N L79 E82 W146 L7 E10 W74
Gene Ontology
Molecular Function
GO:0004176 ATP-dependent peptidase activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6h23, PDBe:6h23, PDBj:6h23
PDBsum6h23
PubMed30129683
UniProtQ16740|CLPP_HUMAN ATP-dependent Clp protease proteolytic subunit, mitochondrial (Gene Name=CLPP)

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