Structure of PDB 6exn Chain N

Receptor sequence
>6exnN (length=242) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
EPPPNICEQCLGDEANIRMTKIPQGSECKICTLPFTLYHFKTSKRSNNII
KTLICVRCATQRNICQCCMLDSRWHIPIQLRDHLISLVNEENVMTEEAKN
DMMKRFLSLKNVKLGGAQITSDPSEADNIVDKLKNILLRKSFFLYNIDAS
IPEWKITDTVSQLLGILSLIVNHKAKCGGLRFQSSELGERFVSKIRGVLL
IDRFRIFIIPWSSGFSAASFGTNTAENIKLSLSLNKLIQLEL
3D structure
PDB6exn Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection.
ChainN
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna N I28 G31 K47 K50 R51 N53 I55 K57 M108 I22 G25 K41 K44 R45 N47 I49 K51 M102
BS02 ZN N C34 C37 C64 C28 C31 C58
BS03 ZN N C71 C74 C65 C68
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0017070 U6 snRNA binding
GO:0036002 pre-mRNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0000974 Prp19 complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0071006 U2-type catalytic step 1 spliceosome
GO:0071007 U2-type catalytic step 2 spliceosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6exn, PDBe:6exn, PDBj:6exn
PDBsum6exn
PubMed29146871
UniProtP38241|SLT11_YEAST Pre-mRNA-splicing factor SLT11 (Gene Name=ECM2)

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