Structure of PDB 4y49 Chain N

Receptor sequence
>4y49N (length=164) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
PINIRRATINDIICMQNANLHNLPENYMMKYYMYHILSWPEASFVATTTT
LDGEKLVGYVLVKMNDDPEPPNGHITSLSVMRTYRRMGIAENLMRQALFA
LREVHQAEYVSLHVRQSNRAALHLYRDTLAFEVLSIEKSYYQDGEDAYAM
KKVLKLEELQISNF
3D structure
PDB4y49 Crystal structure of yeast N-terminal acetyltransferase (ppGpp) NatE in complex with a bisubstrate
ChainN
Resolution3.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.255: N-terminal amino-acid N(alpha)-acetyltransferase NatA.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide N E26 Y28 T116 Y180 E25 Y27 T76 Y140
BS02 CMC N S117 L118 S119 V120 R125 R126 G128 A130 E131 V154 A160 A161 L164 S77 L78 S79 V80 R85 R86 G88 A90 E91 V114 A120 A121 L124
Gene Ontology
Molecular Function
GO:0004596 peptide alpha-N-acetyltransferase activity
GO:0005515 protein binding
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0042802 identical protein binding
GO:1990189 peptide-serine-alpha-N-acetyltransferase activity
GO:1990190 peptide-glutamate-alpha-N-acetyltransferase activity
Biological Process
GO:0006474 N-terminal protein amino acid acetylation
Cellular Component
GO:0005737 cytoplasm
GO:0031415 NatA complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4y49, PDBe:4y49, PDBj:4y49
PDBsum4y49
PubMed
UniProtP07347|ARD1_YEAST N-terminal acetyltransferase A complex catalytic subunit ARD1 (Gene Name=ARD1)

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