Structure of PDB 4tvx Chain N

Receptor sequence
>4tvxN (length=358) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
SNFINIHVLISHSPSCLNRDDMNMQKDAIFGGKRRVRISSQSLKRAMRKS
GYYAQNIGESSLRTIHLAQLRDVLRQKLGERFDQKIIDKTLALLSGKSVD
EEKISADAVTPWVVGEIAWFCEQVAKAEADNLDDKKLLKVLKEDIAAIRV
NLQQGVDIALSGRMATSGMMTELGKVDGAMSIAHAITTHQVDSDIDWFTA
VDDLQEQGSAHTQEFSSGVFYRYANINLAQLQENLGGASREQALEIATHV
VHMLATEVPGAKQRTYAAFNPADMVMVNFSDMPLSMANAFEKAVKAKDGF
LQPSIQAFNQYWDRVANGYGLNGAAAQFSLSDVDPITAQVKQMPTLEQLK
SWVRNNGE
3D structure
PDB4tvx Structural biology. Crystal structure of the CRISPR RNA-guided surveillance complex from Escherichia coli.
ChainN
Resolution3.24 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna N N19 R20 D22 K27 S40 Q42 S43 K45 R46 R49 G164 M166 N18 R19 D21 K26 S39 Q41 S42 K44 R45 R48 G162 M164
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0071667 DNA/RNA hybrid binding
Biological Process
GO:0051607 defense response to virus
GO:0099048 CRISPR-cas system
Cellular Component
GO:0032991 protein-containing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4tvx, PDBe:4tvx, PDBj:4tvx
PDBsum4tvx
PubMed25103409
UniProtQ46899|CASC_ECOLI CRISPR system Cascade subunit CasC (Gene Name=casC)

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