Structure of PDB 2rkj Chain N

Receptor sequence
>2rkjN (length=367) Species: 5141 (Neurospora crassa) [Search protein sequence]
PKYTAKINEAEENWQARAEAIKKGKKQNTWDLFEERGYVKDTAGTKEHIA
ELMRTRRIGAYVGIDPTAPSLHVGHLLPLMPLFWMYLEGYKAFTLIGGST
AKIGDPTGDATMNMTKIHYQLKKLWENVDTQMRARGYEADWARKRGIVNN
NHWWNKQPMLEVLRRVGHALRIGPMLSRDTVKNKMTQGDGVSFAEFTYPI
MQGWDWFELFYQQGVQMQIGGSDQYGNIISGLEVVKAARESEPDPQERKY
VTPKTALDECVGFTVPLLTDSSGAKFGKSAGNAIWLDPYQTSVFDFYGYF
VRRSDQEVENLLKLFTFMPISEITKTMEEHIKDPSKRVAQHTLAREVVTL
VHGKQEASAAEDQHRMM
3D structure
PDB2rkj Structure of a tyrosyl-tRNA synthetase splicing factor bound to a group I intron RNA.
ChainN
Resolution4.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T105 H110 H113 Q251 D272 K324 K327 S328
Catalytic site (residue number reindexed from 1) T67 H72 H75 Q202 D223 K275 K278 S279
Enzyme Commision number 6.1.1.1: tyrosine--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna N P39 K40 K44 H167 K171 R182 W190 R194 G195 I196 H201 Q261 Q262 P292 D293 P294 Q295 P1 K2 K6 H118 K122 R133 W141 R145 G146 I147 H152 Q212 Q213 P243 D244 P245 Q246
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004831 tyrosine-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006437 tyrosyl-tRNA aminoacylation

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Molecular Function
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Biological Process
External links
PDB RCSB:2rkj, PDBe:2rkj, PDBj:2rkj
PDBsum2rkj
PubMed18172503
UniProtP12063|SYYM_NEUCR Tyrosine--tRNA ligase, mitochondrial (Gene Name=cyt-18)

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