Structure of PDB 7qvp Chain MU

Receptor sequence
>7qvpMU (length=101) Species: 9606 (Homo sapiens) [Search protein sequence]
QVLKFTLDCTHPVEDGIMDAANFEQFLQERIKVNGKAGNLGGGVVTIERS
KSKITVTSEVPFSKRYLKYLTKKYLKKNNLRDWLRVVANSKESYELRYFQ
I
3D structure
PDB7qvp A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation.
ChainMU
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna MU R46 K48 S79 K80 R81 Y82 Y85 K89 K92 K93 R97 R101 V103 A104 K107 Y110 R113 R30 K32 S63 K64 R65 Y66 Y69 K73 K76 K77 R81 R85 V87 A88 K91 Y94 R97
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0008201 heparin binding
GO:0042802 identical protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0046632 alpha-beta T cell differentiation
GO:0140236 translation at presynapse
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005925 focal adhesion
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0045202 synapse
GO:0070062 extracellular exosome
GO:0098793 presynapse
GO:0098978 glutamatergic synapse
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:7qvp, PDBe:7qvp, PDBj:7qvp
PDBsum7qvp
PubMed36302773
UniProtP35268|RL22_HUMAN Large ribosomal subunit protein eL22 (Gene Name=RPL22)

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