Structure of PDB 6b4v Chain MB

Receptor sequence
>6b4vMB (length=174) Species: 262724 (Thermus thermophilus HB27) [Search protein sequence]
SRIGRLPIPVPKGVSVEVAPGRVKVKGPKGELEVPVSPEMRVVVEEGVVR
VERPSDERRHKSLHGLTRTLIANAVKGVSEGYSKELLIKGIGYRARLVGR
ALELTVGFSHPVVVEPPEGITFEVPEPTRVRVSGIDKQKVGQVAANIRAI
RKPSAYHEKGIYYAGEPVRLKPGK
3D structure
PDB6b4v Mechanism of Inhibition of Translation Termination by Blasticidin S.
ChainMB
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna MB S2 R3 I4 R6 R59 K62 S63 G66 L67 T70 K85 F109 S110 H111 Q139 G142 Q143 R152 Y157 H158 K160 K172 K175 S1 R2 I3 R5 R58 K61 S62 G65 L66 T69 K84 F108 S109 H110 Q138 G141 Q142 R151 Y156 H157 K159 K171 K174
BS02 MG MB E46 E47 E45 E46
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6b4v, PDBe:6b4v, PDBj:6b4v
PDBsum6b4v
PubMed29366636
UniProtQ72I19|RL6_THET2 Large ribosomal subunit protein uL6 (Gene Name=rplF)

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