Structure of PDB 8yvp Chain M

Receptor sequence
>8yvpM (length=231) Species: 10090 (Mus musculus) [Search protein sequence]
DRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPL
MEPSSIEKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMT
VESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDP
SGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAIKSSLIILKQVMEE
KLNATNIELATVQPGQNFHMFTKEELEEVIK
3D structure
PDB8yvp Optimization of alpha-amido boronic acids via cryo-electron microscopy analysis: Discovery of a novel highly selective immunoproteasome subunit LMP7 ( beta 5i)/LMP2 ( beta 1i) dual inhibitor.
ChainM
Resolution2.5 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1L0D M N98 F101 N90 F93
Gene Ontology
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005839 proteasome core complex
GO:0019773 proteasome core complex, alpha-subunit complex

View graph for
Cellular Component
External links
PDB RCSB:8yvp, PDBe:8yvp, PDBj:8yvp
PDBsum8yvp
PubMed38906067
UniProtQ9Z2U1|PSA5_MOUSE Proteasome subunit alpha type-5 (Gene Name=Psma5)

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