Structure of PDB 8ud9 Chain M

Receptor sequence
>8ud9M (length=212) Species: 9606 (Homo sapiens) [Search protein sequence]
FSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTV
IGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRF
FPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDN
QVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVYTGDALRICIVTKE
GIREETVSLRKD
3D structure
PDB8ud9 Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium proteasome inhibitors
ChainM
Resolution2.04 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.25.1: proteasome endopeptidase complex.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 YRE M R100 D125 S129 R99 D124 S128
Gene Ontology
Biological Process
GO:0051603 proteolysis involved in protein catabolic process
Cellular Component
GO:0005839 proteasome core complex

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Biological Process

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Cellular Component
External links
PDB RCSB:8ud9, PDBe:8ud9, PDBj:8ud9
PDBsum8ud9
PubMed38097652
UniProtP20618|PSB1_HUMAN Proteasome subunit beta type-1 (Gene Name=PSMB1)

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