Structure of PDB 8u5h Chain M

Receptor sequence
>8u5hM (length=95) Species: 8355 (Xenopus laevis) [Search protein sequence]
KTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRL
AHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
3D structure
PDB8u5h Cryo-EM structure of human DNMT3A N-terminal domain bound to H2AK119Ub nucleosome
ChainM
Resolution3.23 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide M Q44 V45 H106 E110 Q17 V18 H79 E83
BS02 dna M R30 K31 S33 Y37 R3 K4 S6 Y10
BS03 dna M T29 Y39 I51 R83 S84 T85 T2 Y12 I24 R56 S57 T58
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:8u5h, PDBe:8u5h, PDBj:8u5h
PDBsum8u5h
PubMed
UniProtP02281|H2B11_XENLA Histone H2B 1.1

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