Structure of PDB 8szn Chain M

Receptor sequence
>8sznM (length=186) Species: 487 (Neisseria meningitidis) [Search protein sequence]
LVPTVIEQRAFDIYSRLLKERIVFLVGPVTDESANLVVAQLLFLESENPD
KDIFFYINSPGGSVTAGMSIYDTMNFIKPDVSTLCLGQAASMGAFLLSAG
EKGKRFALPNSRIMIHQPLISGGQASDIEIHARELLKIKEKLNRLMAKHC
DRDLADLERDTDRDNFMSAEEAKEYGLIDQILENRA
3D structure
PDB8szn Structure-Based Design and Development of Phosphine Oxides as a Novel Chemotype for Antibiotics that Dysregulate Bacterial ClpP Proteases.
ChainM
Resolution2.33 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 X3O M R27 E31 F65 Y67 L95 L119 L196 R199 R16 E20 F54 Y56 L84 L108 L182 R185
BS02 X3O M L53 S57 T84 F87 L42 S46 T73 F76
External links
PDB RCSB:8szn, PDBe:8szn, PDBj:8szn
PDBsum8szn
PubMed39221504
UniProtQ9JZ38|CLPP_NEIMB ATP-dependent Clp protease proteolytic subunit (Gene Name=clpP)

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