Structure of PDB 8syl Chain M

Receptor sequence
>8sylM (length=123) Species: 562 (Escherichia coli) [Search protein sequence]
MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRG
KVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIF
GPVTRELRSEKFMKIISLAPEVL
3D structure
PDB8syl Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome.
ChainM
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna M N13 P48 R49 R98 N13 P48 R49 R98
BS02 rna M M1 Q3 E4 Q5 T6 I22 K23 L25 G27 S28 H29 R30 R31 Y32 K40 T42 K44 V57 K66 K67 R70 N82 M1 Q3 E4 Q5 T6 I22 K23 L25 G27 S28 H29 R30 R31 Y32 K40 T42 K44 V57 K66 K67 R70 N82
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8syl, PDBe:8syl, PDBj:8syl
PDBsum8syl
PubMed37537169
UniProtP0ADY3|RL14_ECOLI Large ribosomal subunit protein uL14 (Gene Name=rplN)

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