Structure of PDB 8sps Chain M

Receptor sequence
>8spsM (length=49) Species: 9606 (Homo sapiens) [Search protein sequence]
NRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKR
3D structure
PDB8sps Structural mechanism of LIN28B nucleosome targeting by OCT4.
ChainM
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna M V276 N280 V38 N42
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0015144 carbohydrate transmembrane transporter activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0008643 carbohydrate transport
GO:0055085 transmembrane transport

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8sps, PDBe:8sps, PDBj:8sps
PDBsum8sps
PubMed37327775
UniProtQ01860|PO5F1_HUMAN POU domain, class 5, transcription factor 1 (Gene Name=POU5F1)

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