Structure of PDB 8ree Chain M

Receptor sequence
>8reeM (length=329) Species: 571 (Klebsiella oxytoca) [Search protein sequence]
AGTPSGNGVGETTQSLQDYLMWQVELTPFTDTDRAIATSIVDAVDDTGYL
TIQIEDIVDSIGDDEIGLEEVEAVLKRIQRFDPVGVAAKDLRDCLLIQLS
QFAKETPWLEEARLIISDHLDLLANHDFRTLMRVTRLKEEVLKEAVNLIQ
SLDPRPGQSIQTGEPEYVIPDVLVRKVNDRWVVELNSDSLPSANDTLLRV
SRCIVEQQQAFFEQGEEYMKPMVLADIAQAVEMHESTISRVTTQKYLHSP
RGIFELKYFFSSHVNTEGGGEASSTAIRALVKKLIAAENPAKPLSDSKLT
SMLSEQGIMVARRTVAKYRESLSIPPSNQ
3D structure
PDB8ree Structural basis of sigma 54 displacement and promoter escape in bacterial transcription.
ChainM
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna M L367 S382 R383 K400 S405 S438 D439 P469 L224 S239 R240 K257 S262 S295 D296 P326
BS02 dna M M376 H377 H406 V407 A454 R456 T457 M233 H234 H263 V264 A311 R313 T314
Gene Ontology
Molecular Function
GO:0001216 DNA-binding transcription activator activity
GO:0016987 sigma factor activity

View graph for
Molecular Function
External links
PDB RCSB:8ree, PDBe:8ree, PDBj:8ree
PDBsum8ree
PubMed38170755
UniProtP06223|RP54_KLEOX RNA polymerase sigma-54 factor (Gene Name=rpoN)

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