Structure of PDB 8osl Chain M

Receptor sequence
>8oslM (length=314) Species: 10090 (Mus musculus) [Search protein sequence]
AKRVSRNKSEKKRRDQFNVLIKELGSMLPGNARKMDKSTVLQKSIDFLRK
HKETTAQSLSNEEFTQLMLEALDGFFLAIMTDGSIIYVSESVTSLLEHLP
SDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEYLKSKNQLEFCCH
MLRGTIDPKEPSTYEYVRFIGNFKSLTRVCFVATVRLATPQFIKEMCTVE
EPNEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLEN
LAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIV
CTHTVVSYAEVRAE
3D structure
PDB8osl Cooperation between bHLH transcription factors and histones for DNA access.
ChainM
Resolution4.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna M K44 D69 K70 K11 D36 K37
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 DNA-binding transcription factor activity
GO:0046983 protein dimerization activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0032922 circadian regulation of gene expression
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8osl, PDBe:8osl, PDBj:8osl
PDBsum8osl
PubMed37407816
UniProtO08785|CLOCK_MOUSE Circadian locomoter output cycles protein kaput (Gene Name=Clock)

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