Structure of PDB 8jay Chain M

Receptor sequence
>8jayM (length=448) Species: 1393122 (Thermoflavifilum thermophilum) [Search protein sequence]
MKELIYIEEPSILFAHGQKCTDPRDGLALFGPLNQIYGIKSGVVGTQKGL
QIFKSYLDKIQKPIYNHNNITRPMFPGFEAVFGCKWESQNIVFKEITDEE
IRRYLFNASTHKRTYDLVTLFNDKIITANKNDEERVDVWFVIVPAQFHDQ
LKARLLEHTIPTQILRESTLAWRDFKNTFGAPIRDFSKIEGHLAWTISTA
AYYKAGGKPWKLGDIRPGVCYLGLVYKKIEKSKNPQNACCAAQMFLDNGD
GTVFKGEVGPWYNPEKGEYHLKPKEAKALLTQALESYKEQNKSYPKEVFI
HARTRFNDEEWNAFNEVTPKNTNLVGVTITKSKPLKLYKTEGAFPIMRGN
AYIVDEKKAFLWTLGFVPKLQSTLSMEVPNPIFIEINKGEAEIQQVLKDI
LALTKLNYNACIYADGEPVTLRFANKIGEILTASTEIKTPPLAFKYYI
3D structure
PDB8jay Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system.
ChainM
Resolution4.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna M I223 R225 F245 L252 N439 N468 D474 G475 R481 I507 I164 R166 F186 L193 N380 N409 D415 G416 R422 I448
BS02 dna M R72 Y285 K286 K287 Y328 R362 T363 R364 M435 R72 Y226 K227 K228 Y269 R303 T304 R305 M376
BS03 MG M N468 I507 N409 I448
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:8jay, PDBe:8jay, PDBj:8jay
PDBsum8jay
PubMed37932527
UniProtA0A1I7NFD7

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