Structure of PDB 8grq Chain M

Receptor sequence
>8grqM (length=84) Species: 9606 (Homo sapiens) [Search protein sequence]
WAHSRAALDRLEKLLRCSRCTNILREPVCLGGCEHIFCSNCVSDCIGTGC
PVCYTPAWIQDLKINRQLDSMIQLCSKLRNLLHD
3D structure
PDB8grq Synthetic E2-Ub-nucleosome conjugates for studying nucleosome ubiquitination.
ChainM
Resolution3.87 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN M C50 C53 C71 C17 C20 C38
BS02 ZN M C66 H68 C86 C33 H35 C53
Gene Ontology
Molecular Function
GO:0003697 single-stranded DNA binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0006301 postreplication repair
GO:0006513 protein monoubiquitination

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Molecular Function
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Biological Process
External links
PDB RCSB:8grq, PDBe:8grq, PDBj:8grq
PDBsum8grq
PubMed
UniProtQ99728|BARD1_HUMAN BRCA1-associated RING domain protein 1 (Gene Name=BARD1)

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