Structure of PDB 8g30 Chain M

Receptor sequence
>8g30M (length=383) Species: 11320 (Influenza A virus) [Search protein sequence]
AEYRNWSKPQCDITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPDKCYQ
FALGQGTTLNNVHSNNTVRDRTPYRTLLMNELGVPFHLGTKQVCIAWSSS
SCHDGKAWLHVCITGDDKNATASFIYNGRLVDSVVSWSKEILRTQESECV
CINGTCTVVMTDGADTKILFIEEGKIVHTSTLSGSAQHVEECSCYPRYPG
VRCVCRDNWKGSNRPIVDINIKDHSIVSSYVCSGLVGDTPRKNDSSSSSH
CLDPNNEEGGHGVKGWAFDDGNDVWMGRTINETSRLGYETFKVIEGWSNP
KSKLQINRQVIVDRGNRSGYSGIFSVEGKSCINRCFYVELIRGRKEETEV
LWTSNSIVVFCGTSGTYGTGSWPDGADLNLMPI
3D structure
PDB8g30 A pan-influenza antibody inhibiting neuraminidase via receptor mimicry.
ChainM
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.18: exo-alpha-sialidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BMA M Q391 I392 R394 Q305 I306 R308
BS02 MAN M Q391 R394 Q305 R308
BS03 CA M D293 G297 D324 G345 H347 D207 G211 D238 G259 H261
Gene Ontology
Molecular Function
GO:0004308 exo-alpha-sialidase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0046761 viral budding from plasma membrane
Cellular Component
GO:0016020 membrane
GO:0033644 host cell membrane
GO:0055036 virion membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8g30, PDBe:8g30, PDBj:8g30
PDBsum8g30
PubMed37258672
UniProtA0A4D6K9W1

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