Structure of PDB 7zs9 Chain M

Receptor sequence
>7zs9M (length=310) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
RGPNLNIVLTCPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDRVGEA
SNPLLDGNNLSTRIGKGETTDMRFTKELNKAQGKNVMDKKDNEVQAAFAK
ITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAASILIGCRR
AEVARTFKEIQSLIHVKTKEFGKTLNIMKNILRGKSEDGFLKIDTDNMSG
AQNLTYIPRFCSHLGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSI
YLNILLFQIPITAAKVGQTLQVTEGTIKSGYKILYEHRDKLVDPQLIANG
VVSLDNLPGV
3D structure
PDB7zs9 Structures of transcription preinitiation complex engaged with the +1 nucleosome.
ChainM
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna M G271 K272 T276 T305 T308 G239 K240 T244 T273 T276
BS02 ZN M C24 C27 C45 C48 C11 C14 C32 C35
Gene Ontology
Molecular Function
GO:0000993 RNA polymerase II complex binding
GO:0001139 RNA polymerase II complex recruiting activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016251 RNA polymerase II general transcription initiation factor activity
GO:0017025 TBP-class protein binding
GO:0046872 metal ion binding
Biological Process
GO:0001113 transcription open complex formation at RNA polymerase II promoter
GO:0001174 transcriptional start site selection at RNA polymerase II promoter
GO:0006352 DNA-templated transcription initiation
GO:0006367 transcription initiation at RNA polymerase II promoter
GO:0010467 gene expression
GO:0051123 RNA polymerase II preinitiation complex assembly
GO:0070897 transcription preinitiation complex assembly
Cellular Component
GO:0005634 nucleus
GO:0097550 transcription preinitiation complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7zs9, PDBe:7zs9, PDBj:7zs9
PDBsum7zs9
PubMed36411341
UniProtP29055|TF2B_YEAST Transcription initiation factor IIB (Gene Name=SUA7)

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