Structure of PDB 7wpr Chain M

Receptor sequence
>7wprM (length=711) Species: 9606 (Homo sapiens) [Search protein sequence]
SSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQNG
KRVSLSVYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKL
SGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGT
LTSDPYDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLK
STSVFARCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEG
MVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINEMCQERCVDGC
SCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWIC
SNEECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIET
VQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGD
LRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNG
NQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMTRF
SEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASY
AAACAGRGVRVAWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEEC
NEACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTMC
YCEDGFMHCTM
3D structure
PDB7wpr Structural basis of von Willebrand factor multimerization and tubular storage.
ChainM
Resolution4.39 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA M D47 N164 N166 F168 D172 D18 N135 N137 F139 D143
BS02 CA M D400 N526 N528 N530 D533 D534 D371 N497 N499 N501 D504 D505
External links
PDB RCSB:7wpr, PDBe:7wpr, PDBj:7wpr
PDBsum7wpr
PubMed35148377
UniProtP04275|VWF_HUMAN von Willebrand factor (Gene Name=VWF)

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