Structure of PDB 7w1o Chain M

Receptor sequence
>7w1oM (length=690) Species: 9823 (Sus scrofa) [Search protein sequence]
SNLIEVFVDGQSVMVEPGTTVLQACEKVGMQIPRFCYHERLSVAGNCRMC
LVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFLLANHPLDC
PICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQ
CTRCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPV
GALTSKPYAFTARPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMH
EDINEEWISDKTRFAYDGLKRQRLTQPMIRNEKGLLTYTTWEDALSRVAG
MLQSFQGNDVAAIAGGLVDAEALVALKDLLNRVDSDSLCTEEVFPTAGAG
TDLRSNYLLNTTIAGVEEADVILLVGTNPRFEAPLFNARIRKSWLHNDLK
VALIGSPVDLTYRYDHLGDSPKILQDIASGNHPFSQILKEAKKPMVVLGS
SALQRSDGTAILAAVSNIAQNIRLSSGVTGDWKVMNILHRIASQVAALDL
GYKPGVEAIRKNPPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAP
MADVILPGAAYTEKSATYVNTEGRAQQTKVAVTPPGLAREDWKIIRALSE
IAGMTLPYDTLDQVRSRLEEVSPNLVRYDDVEGANYFQQANELSKLVNQQ
LLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGI
3D structure
PDB7w1o The coupling mechanism of mammalian mitochondrial complex I.
ChainM
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 M H124 D127 C128 C131 Q133 C137 Q140 V228 H96 D99 C100 C103 Q105 C109 Q112 V200
BS02 SF4 M M173 C176 I177 Q178 C179 T180 R181 C182 C226 L231 M145 C148 I149 Q150 C151 T152 R153 C154 C198 L203
BS03 FES M R62 C64 G73 C75 R76 C78 C92 R34 C36 G45 C47 R48 C50 C64
BS04 MG M Q133 C226 Q105 C198
Gene Ontology
Molecular Function
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0016491 oxidoreductase activity
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0042773 ATP synthesis coupled electron transport
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:7w1o, PDBe:7w1o, PDBj:7w1o
PDBsum7w1o
PubMed35145322
UniProtA0A4X1V1H9

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